Gbp5 protein sources

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August undefined, 2024

WebFeb 2, 2024 · In the same protein, an increased z-score from −3.23 to −1.19 was noted, whereas for the mutant-type protein, the z-score changed from −3.24 to −1.16. For the 891 amino acid variant, the R804C substitution does not alter the secondary structure, but this substitution leads to the expansion of cavity volume by 99.792 Å 3 . WebMar 26, 2024 · Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in positive regulation of cytokine production and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-gamma and response to bacterium. Located in cytoplasmic vesicle. …

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WebMar 29, 2024 · Reviewed by Emily Henderson, B.Sc. Mar 29 2024. New research led by scientists at Washington State University has found that a protein known as GBP5 … WebGBP5. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. phenylalanin worin enthalten

The protein expression of GBP5 in several human

WebGBP5 Protein Overview. By serologic screening of a cutaneous T-cell lymphoma (CTCL) cDNA library, followed by RT-PCR and 3-prime RACE, Fellenberg et al. (2004) cloned … WebMar 29, 2024 · SPOKANE, Wash. – New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in … WebMar 21, 2024 · GeneCards Summary for GBP5 Gene. GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Among its related pathways are Interferon gamma signaling and Cytokine Signaling in Immune system . Gene Ontology (GO) annotations related to this … G6PD (Glucose-6-Phosphate Dehydrogenase) is a Protein Coding … TGFBI (Transforming Growth Factor Beta Induced) is a Protein Coding gene. … SPATA5 (Spermatogenesis Associated 5) is a Protein Coding gene. Diseases … PTPRC (Protein Tyrosine Phosphatase Receptor Type C) is a Protein Coding … phenylalanin therapie

GBP5 promotes liver injury and inflammation by inducing …

Gbp5 protein sources

Tissue expression of GBP5 - Summary - The Human Protein Atlas

WebJun 2, 2024 · NLRP3 inflammasome is implicated in the pathogenesis of inflammatory bowel diseases (IBD). Since guanylate-binding protein 5 (GBP5) induces the NLRP3 inflammasome activity, we aim to investigate the potential role of GBP5 in IBD pathogenesis. The expression of GBP5, NLRP3 inflammasome, and related cytokines … WebAmong the remaining candidates, only GBP5 was specific to M1 and M1( − ) at the protein level ( Figure 6). GBP5 belongs to the family of IFN-γ-induced p65 GTPases, which are well known for ...

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WebOur data demonstrate that GBP5 expression is induced by toxins or the NIK signaling pathway, which promotes both extrinsic and intrinsic apoptosis signaling pathways and further induces liver injury, providing a novel drug … WebExpression of GBP5 in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.

WebProtein Aliases: GBP-5; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; Guanylate-binding protein 5 Gene Aliases: GBP-5; GBP5; UNQ2427/PRO4987 UniProt ID: (Human) Q96PP8 Entrez Gene ID: (Human) 115362 Molecular Function: heterotrimeric G-protein Function (s) WebGuanylate binding protein 5 (HGNC Symbol) Entrez gene summary: This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an …

WebConsistent with extensive gene/protein characterization data. RNA consistency i Consistency between immunohistochemistry data and consensus RNA levels is divided into five different categories: i) High consistency, ii) Medium consistency, iii) Low consistency, iv) Very low consistency, and v) Cannot be evaluated. WebFeb 19, 2024 · Human guanylate binding protein 5 (GBP5) belongs to the dynamin superfamily of interferon-gamma-inducible large GTPases 3, ... and the source, provide …

WebThe three protein domains shown were identified from the human GBP5 protein as annotated at Ensembl in release 77. The box shown in orange corresponds to the p-loop containing nucleoside...

WebMay 28, 2015 · The GBP5 protein is an important mediator of inflammatory immune response in mammals. Loss of GBP5 function in a knockout mouse model results in impaired host defense and inflammatory response because GBP5 facilitates nucleotide binding and oligomerization, leucine-rich repeat protein 3 (NLRP3) mediated … phenylalanine absorbanceWebMar 29, 2024 · GBP5 is constitutively localized in the Golgi apparatus of endothelial cells. 3 genes were upregulated in patients with chronic EBV infection: guanylate binding protein 1, tumor necrosis factor-induced protein 6, and guanylate binding protein 5; they may be associated with the inflammatory reaction or with cell proliferation. phenylalanin-tyrosin-stoffwechselWebIn this study, an ELISA for detecting whole blood GBP5 protein was developed, and it was found that the levels of whole blood GBP5 protein have the potential to dierentiate aTB from non-TB. phenylalanine 4-hydroxylaseWebDec 27, 2024 · Gbp5 mRNA and protein levels were measured by qPCR and Western blot (n = 3–6). (H) Primary hepatocytes were treated with TNFα (10 ng/ml), IFNγ (100 ng/ml), and TNFα plus IFNγ for 12 h, respectively. Gbp5 mRNA and protein levels were measured by qPCR and Western blot. *p < .05. **p < .01. Data represent the mean ± SEM phenylalanine acidic or basicWeb14 results. Get better value for money with our 5kg Protein Powders! From Whey Isolates to Weight Gainers, we've got your bulk orders of protein covered. Log in/sign up to use … phenylalanine agar testWebApr 13, 2016 · Guanylate binding proteins (GBPs) are an interferon (IFN)-inducible subfamily of guanosine triphosphatases (GTPases) with well-established activity against … phenylalanin tyrosin stoffwechselWebDec 1, 2001 · GBP5. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 586. ... identical protein binding Source:IntAct. 3 publications. … phenylalanine acid or base