Bongkrekic acid-13c28
WebJul 9, 2015 · Bongkrekic Acid In humans though, toxicity manifests within a few hours of ingestion and presents with abdominal pain, general discomfort, sweating, fatigue, and eventual coma. Death can occur within 24 hours. WebMolecular Weight: 486.61 (free acid) Molecular Formula: C 28 H 38 O 7 Solubility: Miscible with DMSO. Physical Properties: Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL) Purity: 97% by HPLC NMR (Conforms) Storage Temperature: -20° Stability: Stable for 1 year from date of purchase as supplied.
Bongkrekic acid-13c28
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WebBongkrekic acid (BKA) is an inhibitor of adenine nucleotide translocase (ANT). Since inhibition of ANT is connected to the inhibition of cytochrome c release from mitochondria, which then results in the suppression of apoptosis, it has been used as a tool for the mechanistic investigation of apoptosis. WebMay 20, 1991 · Here we demonstrate that bongkrekic acid, a potent inhibitor of the mitochondrial ATP/ADP translocase, inhibits glucose-induced electrical activity in the pancreatic β-cell through the simulation of ATP-sensitive potassium channel (K-ATP-channel) activity.
WebSep 20, 2024 · Bongkrekic acid is produced by the bacterium, Burkholderia cocovenenans, which is ubiquitous in the soil and plants. It grows best at 37°C and can optimally produce bongkrekic acid at about 26°C. Bongkrekic acid is heat-stable and cannot be removed by washing. Patients suffering from bongkrekic acid poisoning may show symptoms … WebIso-bong: A versatile first synthesis of isobongkrekic acid (IBA) has been developed. Key steps include three different palladium cross-couplings and an asymmetric homopropargylation. In-depth synthetic studies reveal the challenges faced in generating the right geometry of each diene. Abstract
WebThe antifungal activity of bongkrekic acid against 17 tested molds was determined. Bongkrekic acid prevented spore germination and mycelial proliferation of Aspergillus … WebMar 1, 1970 · The antibiotic bongkrekic acid is shown to inhibit the phosphorylation of added ADP coupled with either the reactions of the respiratory chain or the dismutation …
WebDec 18, 2024 · Poisoning incidents caused by bongkrekic acid (BA), one of the metabolites of Burkholderia gladioli pathovar cocovenenans ( B. cocovenenans ), have been reported in Indonesia, Mozambique, and China. The reported case fatality rates averaged 60%, 32%, and 26.5%, respectively.
WebBongkrekic acid is a mitochondrial ANT toxin and is reported primarily in outbreaks of food-borne poisoning involving coconut and corn. It should be considered in outbreaks of food … gold cost in india today1 gramWebBongkrekic acid is a little-known toxin and source of food poisoning that is produced by the bacterium Burkholderia gladioli. These bacteria flourish … hcl thermofisherWebJan 19, 2024 · Bongkrekic acid (BA), a little-known mitochondrial toxin produced by the bacterium Burkholderia gladioli pathovar (strain or set of strains with the same or similar … gold cost per 100gWebBongkrekic acid C28H38O7 CID 6433556 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. gold cost ounceWebMay 1, 2002 · Mitochondrial Delivery of Bongkrekic Acid Using a MITO-Porter Prevents the Induction of Apoptosis in Human HeLa Cells. Journal of Pharmaceutical Sciences 2013, 102 (3) , 1008-1015. hcl thermometerWebBongkrekic acid (BA) poisoning can be caused by eating spoiled or fermented foods contaminated with pseudomonas cocovenenans. Although some in vitro studies have … hcl thermodynamic dataWebBongkrekic acid affects the liver, brain and kidneys, causing symptoms including lack of energy, dizziness, drowsiness, abdominal pain, vomiting etc. In severe cases, consuming food contaminated with Bongkrekic acid can be life threatening. What is SFA doing to reduce food safety risks from Bongkrekic Acid? gold cost per gram 14k